Flotillin family protein
Webtillin-1 and flotillin-2 were substantially reduced on both mRNA and protein levels by siRNA transfection (Fig. 2 A and B). Knockdown of flotillin-1 or flotillin-2 led to the … WebOct 25, 2011 · There are two homologous members in flotillin proteins family, flotillin-1 and flotillin-2. ... Hazarika et al. found that both flotillin-2 protein and mRNA were increased in tumorigenic and metastatic melanoma cell lines in vitro. SB2 melanoma cells altered to highly tumorigenic and metastatic in nude mice after transfection of flotillin-2.
Flotillin family protein
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WebFlotillin-1 is a close homolog of the Epidermal Surface Antigen (ESA/Flotillin-2), which also colocalizes in the caveolae. Thus, Flotillin-1 and its relative ESA/Flotillin-2 are now … WebNov 27, 2009 · Calcium spiking appears to control activity of a calcium/calmodulin-dependent protein kinase and two downstream GRAS-family transcription factors, NSP1 and NSP2, which interact in the plant nucleus and directly bind the ... which contains the protein flotillin . Flotillins [also called Reggies (11)] are often used as markers for ...
Webanalysis of the cDNA for this protein has provided new avenues by which to explore the structure and function of caveolae organelles. Interestingly, flotillin is a close homologue … WebMar 1, 2008 · The flotillin-2 protein induction was observed as early as 12 hours after TAp73β or TAp63γ overexpression. Even when Saos-2 cells were infected with Ad-p53 …
WebFeb 9, 2024 · The flotillin (FLOT)/reggie protein family is integral membrane element and contains two isoforms: flotillin-1 (reggie-2) and flotillin-2 ... Here, we demonstrate that the scaffold protein flotillin-1 … WebDuring Hepatitis C virus (HCV) morphogenesis, the non-structural protein 2 (NS2) brings the envelope proteins 1 and 2 (E1, E2), NS3, and NS5A together to form a complex at the endoplasmic reticulum (ER) membrane, initiating HCV assembly. The nature of the interactions in this complex is unclear, but replication complex and structural proteins …
WebFlotillin-1 Antibody detects endogenous levels of total flotillin-1 protein. Species Reactivity: Human, Mouse, Rat, Monkey. ... Flotillins belong to a family of lipid raft-associated integral membrane proteins that carry an …
WebSep 10, 2014 · The flotillin protein family consists of flotillin-1 and 2 (also called reggies) which homo- and hetero-oligomerize [2, 37]. Despite some other functions [ 4 , 32 ], flotillins have been linked to endocytosis and vesicular trafficking but also to signaling [ 6 , 8 , 14 , 15 , 24 , 33 , 36 , 38 ]. irrational buffoon\u0027s european vacationWebFLOT1. Flotillin-1 is a protein that in humans is encoded by the FLOT1 gene. [5] Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal … portable camping heaterWebApr 13, 2024 · Patellins, a protein family that has PI-binding activity, have been identified in plant-derived EVs, providing a basis for this hypothesis that requires future investigation. FCW = fungal cell wall, FM = fungal membrane, FMT = fungal memtub, FLOT/REM = flotillin/remorin, LE = late endosome, PCW = plant cell wall, PATL = patellin, PS = … portable camping gas stove single burnerWebMar 26, 2024 · Flotillin-1 and flotillin-2 are ubiquitously expressed, membrane-associated proteins involved in multifarious cellular events from cell signaling, endocytosis, and … irrational and rational number rulesirrational anxiety causesWebOct 20, 2024 · For FLOT1-/FLOT2-positive early endosomes, we identify >300 putative cargo proteins and confirm eleven substrates for flotillin-dependent endocytosis, including the latrophilin family of adhesion ... portable camping power systemsWebOct 4, 2005 · May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. Sequence similarities. Belongs to the band 7/mec-2 family. Flotillin subfamily. Cellular localization. Cell membrane. Membrane > caveola. Melanosome. Endosome. Membrane-associated … irrational crossword clue dan word