WebChIPBase v2.0 is an open database for studying the transcription factor binding sites and motifs, and decoding the transcriptional regulatory networks of lncRNAs, miRNAs, other ncRNAs and protein-coding genes from ChIP-seq data. Our database currently contains ~10,200 curated peak datasets derived from ChIP-seq methods in 10 species.. We … WebAug 8, 2024 · 用snapgene软件打开此序列:. 用snapgene软件打开对应的NM转录本(import导出),复制第一个外显子在基因组序列搜索,其上序列就是启动子座落区,复制出来即可。. 二、转录因子预测. 1. Jaspar预测. 打开Jaspar网站,在搜索框里输入转录因子名称,“搜索”,按照 ...
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WebJan 12, 2024 · 转录调控是生命活动中重要的调控机制,通过chip_seq数据,我们可以得到转录因子或者组蛋白修饰和基因之间的调控关系。chipBase数据库收集了来自10个物种共一万多个样本的chip_seq数据, … WebMay 22, 2024 · Studies on biological functions of N 6-methyladenosine (m 6 A) modification in mRNA have sprung up in recent years. We find m 6 A can positively regulate the glycolysis of cancer cells. Specifically, m 6 A-sequencing and functional studies confirm that pyruvate dehydrogenase kinase 4 (PDK4) is involved in m 6 A regulated glycolysis and … how many kids does elizabeth taylor have
ChIPBase v2.0: Decoding Transcriptional Regulactory Networks of …
WebNational Center for Biotechnology Information WebJun 1, 2024 · Databases like Expresso and ChIPBASE2.0 were developed in order to predict regulators of input genes based on ChIP-Seq data [1, 70]. The users can upload … WebThe molecular regulatory network underlying stem cell pluripotency has been intensively studied, and we now have a reliable ensemble model for the “average” pluripotent cell. However, evidence of significant cell-to-cell variability suggests that the activity of this network varies within individual stem cells, leading to differential processing of … how many kids does error and ink have